In-Vivo Phenotypic Screens Identify Therapeutic Targets for Common Pathological Problems in Neurological Disorders

Time: 9:30 am
day: Day One


  • In vivo phenotypic screens identify therapeutic targets underlying common
    pathological problems in neurodegenerative and neurological disorders
  • Neurotrauma-related degeneration causes excitation/inhibition imbalance in spared
    nervous system tissue, but KCC2-enhancing therapies can restore lost functions
  • KCC2-enhancing treatments are promising therapies for rare and genetic disorders
    involving excitation/inhibition imbalance and neuronal circuit disinhibition in the CNS