AAV-DNase I Delivery Targeting Extracellular DNA as a New Strategy for Treatment of Alzheimer’s Disease

Time: 2:00 pm
day: Day Two


  • Extracellular DNA from different bacterial species can act as a virulence factor triggering prion-like aggregation
  • Bacterial DNA can participate in the cross-kingdom protein misfolding, leading to the aggregation of tau and beta-amyloid proteins.
  • Extracellular DNA as a new therapeutic target for the treatment of neurodegenerative diseases.